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Takuji Tanaka Selected Research

Dextrans (Dextran)

1/2022Suppression of C-C chemokine receptor 1 is a key regulation for colon cancer chemoprevention in AOM/DSS mice by fucoxanthin.
12/2021Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis.
3/2021Fucoxanthin Prevents Colorectal Cancer Development in Dextran Sodium Sulfate-treated Apc Min/+ Mice.
11/2020Continuity of Tumor Microenvironmental Suppression in AOM/DSS Mice by Fucoxanthin May Be Able to Track With Salivary Glycine.
10/2016Different Susceptibilities between Apoe- and Ldlr-Deficient Mice to Inflammation-Associated Colorectal Carcinogenesis.
2/2016Cimetidine and Clobenpropit Attenuate Inflammation-Associated Colorectal Carcinogenesis in Male ICR Mice.
8/2014A newly synthesized compound, 4'-geranyloxyferulic acid-N(omega)-nitro-L-arginine methyl ester suppresses inflammation-associated colorectal carcinogenesis in male mice.
1/2014A novel aromatic mutagen, 5-amino-6-hydroxy-8H-benzo[6,7]azepino[5,4,3-de]quinolin-7-one (ABAQ), induces colonic preneoplastic lesions in mice.
4/2013Tumor suppressor APC protein is essential in mucosal repair from colonic inflammation through angiogenesis.
1/2012Development of an inflammation-associated colorectal cancer model and its application for research on carcinogenesis and chemoprevention.
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Takuji Tanaka Research Topics

Disease

135Carcinogenesis
01/2022 - 01/2001
109Neoplasms (Cancer)
05/2022 - 02/2002
58Inflammation (Inflammations)
05/2022 - 11/2003
46Body Weight (Weight, Body)
02/2017 - 02/2002
43Adenocarcinoma
01/2022 - 03/2002
38Colonic Neoplasms (Colon Cancer)
01/2022 - 09/2002
30Colitis
12/2021 - 10/2003
25Colorectal Neoplasms (Colorectal Cancer)
12/2021 - 09/2008
23Obesity
08/2017 - 01/2008
18Aberrant Crypt Foci
12/2014 - 02/2002
14Hepatocellular Carcinoma (Hepatoma)
11/2021 - 01/2005
10Carcinoma (Carcinomatosis)
01/2010 - 05/2002
9Adenoma (Adenomas)
06/2017 - 09/2002
9Insulin Resistance
01/2015 - 05/2009
7Tongue Neoplasms (Tongue Neoplasm)
03/2007 - 05/2002
6Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/2014 - 05/2002
5Fatty Liver
09/2017 - 01/2011
5Fibrosis (Cirrhosis)
03/2017 - 09/2012
4Ulcerative Colitis
01/2019 - 10/2003
4Alcoholic Fatty Liver
09/2018 - 03/2016
4Liver Neoplasms (Liver Cancer)
08/2017 - 05/2009
4Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
06/2017 - 09/2002
4Diabetes Mellitus
03/2016 - 10/2007
4Prostatic Neoplasms (Prostate Cancer)
09/2014 - 03/2002
4Hyperlipidemias (Hyperlipidemia)
07/2014 - 10/2007
4Infections
07/2013 - 01/2007
4Urinary Bladder Neoplasms (Bladder Cancer)
01/2011 - 01/2002
3Ovarian Neoplasms (Ovarian Cancer)
02/2022 - 05/2002
3Pancreatic Neoplasms (Pancreatic Cancer)
12/2021 - 03/2012
3Lymphoma (Lymphomas)
11/2018 - 08/2007
3Non-alcoholic Fatty Liver Disease
08/2017 - 01/2013
3Disease Progression
06/2017 - 03/2006
3Liver Cirrhosis (Hepatic Cirrhosis)
03/2017 - 02/2010
3Hyperinsulinism (Hyperinsulinemia)
03/2016 - 05/2009

Drug/Important Bio-Agent (IBA)

56AzoxymethaneIBA
01/2022 - 02/2002
39Drinking WaterIBA
01/2019 - 05/2002
32sodium sulfate (sodium bisulfate)FDA LinkGeneric
01/2022 - 10/2003
31Dextrans (Dextran)FDA Link
01/2022 - 10/2003
30Proteins (Proteins, Gene)FDA Link
01/2022 - 09/2002
19beta CateninIBA
07/2010 - 09/2002
18Dextran SulfateIBA
01/2021 - 02/2005
16EnzymesIBA
11/2021 - 01/2001
15AntioxidantsIBA
03/2016 - 01/2001
13CarcinogensIBA
05/2021 - 01/2001
13Proliferating Cell Nuclear Antigen (PCNA)IBA
09/2018 - 02/2002
12CytokinesIBA
05/2022 - 02/2005
12fucoxanthinIBA
01/2022 - 11/2004
12Diethylnitrosamine (N-Nitrosodiethylamine)IBA
08/2017 - 01/2004
10Messenger RNA (mRNA)IBA
06/2017 - 02/2006
9Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2022 - 10/2003
9Biomarkers (Surrogate Marker)IBA
11/2021 - 10/2003
9TeaIBA
04/2017 - 05/2008
8Carotenoids (Carotene)IBA
12/2021 - 11/2004
8Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2014 - 11/2003
8FlavonoidsIBA
01/2012 - 01/2001
7AdipokinesIBA
03/2016 - 05/2008
7Peroxisome Proliferator-Activated Receptors (PPAR)IBA
05/2014 - 04/2003
7Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2012 - 01/2003
7auraptenIBA
02/2010 - 01/2004
7PPAR gammaIBA
05/2007 - 04/2003
6LigandsIBA
12/2021 - 04/2003
6Biological ProductsIBA
11/2021 - 01/2008
6Dinoprostone (PGE2)FDA Link
01/2021 - 01/2004
6LipidsIBA
07/2017 - 06/2004
6CateninsIBA
06/2017 - 06/2011
6Branched-Chain Amino AcidsIBA
03/2017 - 05/2009
6Insulin (Novolin)FDA Link
01/2015 - 05/2004
5PhytochemicalsIBA
04/2017 - 01/2001
5Pharmaceutical PreparationsIBA
04/2017 - 07/2004
5pitavastatin (itavastatin)FDA Link
07/2014 - 11/2007
5SilymarinIBA
10/2011 - 01/2002
5nobiletinIBA
01/2011 - 01/2004
5Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
03/2007 - 06/2004
5CyclinsIBA
02/2007 - 04/2003
5alpha-Linolenic Acid (Linolenic Acid)IBA
11/2006 - 02/2002
4fucoxanthinolIBA
05/2021 - 07/2017
4Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
01/2021 - 01/2013
4(2E,4E,6E,10E)- 3,7,11,15- tetramethyl- 2,4,6,10,14- hexadecapentaenoic acidIBA
06/2017 - 06/2004
4astaxanthine (astaxanthin)IBA
03/2016 - 08/2011
4Insulin-Like PeptidesIBA
05/2014 - 09/2008
4IGF Type 1 Receptor (IGF 1 Receptor)IBA
05/2014 - 05/2009
4SesquiterpenesIBA
03/2013 - 10/2003
4Interleukin-6 (Interleukin 6)IBA
03/2013 - 01/2011
4Glutathione Transferase (Glutathione S-Transferase)IBA
01/2013 - 01/2003
4Prostaglandins EIBA
08/2011 - 05/2002
4benzocycloheptapyridineIBA
01/2011 - 01/2005
42- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA
01/2011 - 01/2005
4LeptinIBA
02/2010 - 05/2004
4DNA (Deoxyribonucleic Acid)IBA
05/2007 - 01/2001
43-nitrotyrosineIBA
06/2006 - 09/2004
3nitrosobis(2-oxopropyl)amine (NBOP)IBA
05/2021 - 06/2004
33,7,11,15- tetramethyl- 2,4,6,10,14- hexadecapentaenoic acidIBA
06/2017 - 01/2011
3platelet-derived growth factor C (PDGF-C)IBA
03/2017 - 09/2012

Therapy/Procedure

45Chemoprevention
01/2022 - 01/2001
18Subcutaneous Injections
09/2017 - 02/2002
14Intraperitoneal Injections
01/2016 - 03/2002
9Therapeutics
05/2022 - 11/2005
4Oral Administration
01/2021 - 01/2009
3Aftercare (After-Treatment)
11/2021 - 09/2002
3Drug Therapy (Chemotherapy)
05/2021 - 03/2012